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Dr. Arpana Vibhuti

Associate Professor & Head
Department of Biotechnology

Education

Degree Specialization University/Institute Name, Year
Ph.D. Biotechnology IGIB, CSIR, Delhi & Savitribai Phule Pune University, 2008
M.Sc. Biotechnology DDU Gorakhpur University, 2002
B.Sc. Zoology, Chemistry, Botany DDU Gorakhpur University, 1999

Research Interests

To investigate the role of telomeres and telomerase activity in adaptation or maladaptation at high altitude hypobaric hypoxia. The relevance of telomere increases because of the prevalence of stress to hypobaric hypoxia at HA. We explored that telomere & telomerase associate differentially in sojourners/natives and may be a potential marker. The study leads for investigation of the association of telomere in extreme environment of hypobaric hypoxia having low pressure, low oxygen and high radiation. Moreover, many diseases are having hypoxia in their pathogenesis including Covid-19 & Cancer. So future research objectives are to investigate the association of telomeres and telomerase associated biomarkers in disease pathogenesis of oxidative stress associated diseases including High Altitude disorders, cancer and Covid-19.

Current Courses Taught / Teaching Interest

Teaching Interest includes preparing innovative learning environment through Problem based teaching, Practical based learning, Industrial Exposure, Workshop & Conference based learning. Specific subject teaching done through various case studies. Teaching & research is reflected through peer reviewed publications, disciplined, attentive & Enthusiastic students, Positive feedbacks from the students. Lectures prepared in form of PPT, Study materials, tutorials & Group discussions of the students. Subjects taught in UG, PG & PhD is given hereby.

Academic Experience / Industrial Experience

  • June 2018 till present-Associate Professor and Head of Biotechnology & Microbiology department at SRM University, Delhi-NCR, Sonepat.
  • Sept 2014 till June 2023- Head of Biomedical engineering department at SRM University, Delhi-NCR, Sonepat.
  • Sept 2014-May2018-Assistant Professor and Head in Biomedical Engineering & Bioinformatics at SRM University, Delhi-NCR, Sonepat.
  • Oct 2013-Sept 2014-Assistant Professor in Biotechnology at Amity University, Haryana.
  • May 2011-Nov 2012-ICMR-RA with Dr. Monica Sundd, Scientist at NII, New Delhi.    
  • June 2009-September 2010-NIH-PDF with Dr Hydar Ali, Associate Professor at University of Pennsylvania (Upenn), Philadelphia, PA, USA.
  • January 2009-June 2009-DBT-PDF with Dr. Dinakar M. Salunke, Senior Scientist at NII, New Delhi.
  • July 2005-Dec 2008-CSIR-SRF with Dr. MA Qadar Pasha, Senior Scientist at IGIB, CSIR, Delhi
  • July 2003-July 2005-CSIR-JRF with Dr. MA Qadar Pasha, Senior Scientist at IGIB, CSIR, Delhi

Achievements / Awards / Recognitions

  • Ongoing DST-SERB-CRG project (CRG/2022/5161) as a Principal Investigator.
  • Successfully completed DST-SERB project (SB/YS/LS-155/2014) as a Principal Investigator.
  • Two Ph.D. awarded & one Ph.D. thesis submission in 2023 as a Ph.D. Supervisor.
  • Corresponding author of high Impact research paper ie. Human Molecular Genetics (IF-6.1) & Drug Discovery Today (IF-7.85)
  • Active member as a Treasurer for Hypobaric hypoxia Society since 2021.
  • Member of editorial board and Reviewer of many peer- reviewed journals.
  • Reviewer of DRDO and Army Mission Projects.
  • External expert in CSIR-IGIB for Research Personal selection.
  • Qualified National Eligibility Test (NET-LS) in Dec-2001 and (NET-JRF) June-2002.
  • Invited talk in International Conferences (2010 & 2018)
  • Qualified Graduate Aptitude Test in Life Sciences (GATE)-2003 with 96 Percentile.
  • Topper and Gold Medalist in M.Sc. Biotechnology 2002.
  • Qualified DBT-Postdoctoral Fellowship Program 2008-2009, Life Sciences.
  • Qualified NIH-Postdoctoral Fellowship Program 2009, for Postdoctoral Research in USA.

R&D / Industrial Projects

  • Research Project of 30 Lakh from Department of Science & Technology (DST, SERB) as a Principal Investigator (PI) for Life Science project entitled “Telomeres and telomerase activity in adaptation towards hypobaric hypoxia.” for 3 Years duration (2015-2018)- Completed.
  • Ongoing Research Project of 43 Lakh from Department of Science & Technology, Core Research Grant (DST, SERB- CRG) as a Principal Investigator (PI) for Life Science project entitled “Deciphering the Methylation Status and expression of telomere and telomerase complex genes under Hypobaric Hypoxia.” for 3 Years duration (2023-2026)

Selected Publications/Working Papers

S. No. Paper Title Journal/Conference International/National Volume/Doi Page No Year
1 Exploration of Antileishmanial Compounds Derived from Natural Sources.  Antiinflamm Antiallergy Agents Med Chem.  International https://doi.org/10.2174/0118715230270724231214112636 13 2024
2 Alleviation of radiation combined skin injury in rat model by topical application of ascorbate formulation.  Int J Radiat Biol International https://doi.org/10.1080/09553002.2024.2310016 689-708 2024
3 A Systematic Assessment of Leishmania donovani Infection in Domestic and Wild Animal Reservoir Hosts of Zoonotic Visceral Leishmaniasis  Preprint International https://doi.org/10.20944/preprints202306.1528.v1 2023
4 Liposomes and phytosomes: Nanocarrier systems and their applications for the delivery of phytoconstituents.  Coordination Chemistry Reviews International https://doi.org/10.1016/j.ccr.2023.215251 215251 2023
5 Therapeutic applications of nanobiotechnology. Journal of Nanobiotechnol  International https://doi.org/10.1186/s12951-023-01909-z 148 2023
6 Silver Nanoparticles Phytofabricated through Azadirachta indica: Anticancer, Apoptotic, and Wound-Healing Properties. Antibiotics International https://doi.org/10.3390/antibiotics12010121 121 2023
7 Synthesis and Biological Characterization of Phyto-Fabricated Silver Nanoparticles from Azadirachta indica Journal of Biomedical Nanotechnology International https://doi.org/10.1166/jbn.2022.3402 2022-2057 2022
8 The Association between Biofilm Formation and Antimicrobial Resistance with Possible Ingenious Bio-Remedial Approaches.  Antibiotics International https://doi.org/10.3390/antibiotics11070930 930 2022
9 Determination of Antioxidants by DPPH Radical Scavenging Activity and Quantitative Phytochemical Analysis of Ficus religiosa Molecules International https://doi.org/10.3390/molecules27041326 1326 2022
10 Protein based therapeutics Book Chapter International https://doi.org/10.1007/978-981-19-8249-1 2022
11 Chitosan: Applications in Drug Delivery System.  Mini Rev Med Chem International https://doi.org/10.2174/1389557522666220609102010 187-191 2022
12 Evaluation of antiviral activity of Andrographis paniculata and Tinospora cordifolia using in silico and in vitro assay against DENV-2 Journal of Pharmacognosy and Phytochemistry International https://doi.org/10.22271/phyto.2021.v10.i2f.13847 2021
13 Seeding Drug Discovery: telomeric tankyrase as a pharmacological target for the pathophysiology of high-altitude hypoxia. Drug Discovery Today  International https://doi.org/10.1016/j.drudis.2021.07.012 2774-2781 2021
14 Potential of nanoparticles encapsulated drugs for possible inhibition of the antimicrobial resistance development Biomedicine &Pharmacothrapy  International https://doi: 10.1016/j.biopha.2021.111943 111943 2021
15 Evaluation of Clinical and Hematological Parameters of Acute Febrile Illness Patients: A Dengue Predictive Model.  J Antivir Antiretrovir, 2021, 13 (001) International 13 2021

Other Information

Postdoctoral Research

  • May 2011-Nov 2012-Worked as an ICMR-RA with Dr. Monica Sundd, Scientist at NII, New Delhi.
  • June 2009-September 2010-Worked as a NIH-PDF with Dr Hydar Ali, Associate Professor at University of Pennsylvania (Upenn), Philadelphia, PA, USA.
  • January 2009-June 2009-Worked as a DBT-PDF with Dr. Dinakar M. Salunke, Senior Scientist at NII, New Delhi.
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